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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TBCC
All Species:
37.58
Human Site:
Y108
Identified Species:
63.59
UniProt:
Q15814
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15814
NP_003183.1
346
39220
Y108
S
V
F
F
L
A
A
Y
D
L
R
Q
G
Q
E
Chimpanzee
Pan troglodytes
XP_518477
346
39236
Y108
S
V
F
F
L
A
A
Y
D
L
R
Q
G
Q
E
Rhesus Macaque
Macaca mulatta
XP_001088723
346
39322
Y108
S
V
F
F
L
A
A
Y
D
L
R
Q
G
Q
Q
Dog
Lupus familis
XP_538923
388
42549
Y150
A
V
L
F
L
A
A
Y
D
L
R
Q
G
Q
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8VCN9
341
38106
Y107
S
V
L
F
L
A
A
Y
D
L
R
Q
G
Q
A
Rat
Rattus norvegicus
NP_001101670
340
38058
Y107
S
V
L
F
L
A
A
Y
D
L
R
Q
G
Q
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508991
335
37102
Y108
A
V
L
F
L
A
P
Y
D
L
R
Q
G
Q
E
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001922489
350
39443
Y110
S
V
R
F
L
T
Q
Y
E
I
R
Q
A
Q
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_722959
355
40503
F103
S
T
M
F
L
P
D
F
K
I
K
S
C
Q
N
Honey Bee
Apis mellifera
XP_001120828
342
39209
Y100
S
K
M
F
L
K
V
Y
D
I
R
R
A
Q
E
Nematode Worm
Caenorhab. elegans
Q27249
256
29613
E45
E
V
K
R
Q
L
E
E
E
R
K
K
R
E
D
Sea Urchin
Strong. purpuratus
XP_783718
353
39965
H122
M
T
Q
F
L
P
S
H
D
I
Q
S
A
Q
N
Poplar Tree
Populus trichocarpa
XP_002307082
324
36492
Y97
S
S
Y
F
L
P
S
Y
E
L
R
S
S
L
K
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_195702
345
38291
Y114
N
S
Y
F
L
P
S
Y
E
V
R
S
S
L
K
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
95.3
72.9
N.A.
76
74.5
N.A.
61.5
N.A.
N.A.
43.7
N.A.
33.5
38.7
21.1
39.6
Protein Similarity:
100
99.1
97.6
78.3
N.A.
84.3
83.5
N.A.
74.5
N.A.
N.A.
64
N.A.
57.7
58
40.1
62.6
P-Site Identity:
100
100
93.3
86.6
N.A.
86.6
86.6
N.A.
80
N.A.
N.A.
60
N.A.
26.6
53.3
6.6
26.6
P-Site Similarity:
100
100
100
93.3
N.A.
86.6
86.6
N.A.
86.6
N.A.
N.A.
73.3
N.A.
46.6
66.6
40
53.3
Percent
Protein Identity:
29.7
N.A.
N.A.
32.3
N.A.
N.A.
Protein Similarity:
48.2
N.A.
N.A.
51.7
N.A.
N.A.
P-Site Identity:
40
N.A.
N.A.
26.6
N.A.
N.A.
P-Site Similarity:
66.6
N.A.
N.A.
66.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
15
0
0
0
0
50
43
0
0
0
0
0
22
0
15
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% C
% Asp:
0
0
0
0
0
0
8
0
65
0
0
0
0
0
8
% D
% Glu:
8
0
0
0
0
0
8
8
29
0
0
0
0
8
43
% E
% Phe:
0
0
22
93
0
0
0
8
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
50
0
0
% G
% His:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
29
0
0
0
0
0
% I
% Lys:
0
8
8
0
0
8
0
0
8
0
15
8
0
0
15
% K
% Leu:
0
0
29
0
93
8
0
0
0
58
0
0
0
15
0
% L
% Met:
8
0
15
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
15
% N
% Pro:
0
0
0
0
0
29
8
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
8
0
8
0
8
0
0
0
8
58
0
79
8
% Q
% Arg:
0
0
8
8
0
0
0
0
0
8
79
8
8
0
0
% R
% Ser:
65
15
0
0
0
0
22
0
0
0
0
29
15
0
0
% S
% Thr:
0
15
0
0
0
8
0
0
0
0
0
0
0
0
0
% T
% Val:
0
65
0
0
0
0
8
0
0
8
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
15
0
0
0
0
79
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _